Causes and risk factors
Cause is hereditary. The disease runs in families. Genetic mutation occurs in β globin gene leading to the disease condition.
Clinical presentation
Patient is mostly asymptomatic. Symptoms include enlargement of spleen, anemia, jaundice. Development of gallstones is observed in some patients.
Investigation
Medical history by the patient and clinical examination by the doctor helps in diagnosis. Complete blood count is done. Hemoglobin electrophoresis is advised. Peripheral blood smear is required.
Treatment
Symptomatic treatment is given for anemia, jaundice. Administration of folic acid supplement is necessary. Cholecystectomy in case of gallstones is needed. Splenectomy may be required.
Other Modes of treatment
The other modes of treatment can also be effective in treating hemoglobin C disease. Homoeopathy is a science which deals with individualization and considers a person in a holistic way. This science can be helpful in combating the symptoms. Similarly, the Ayurvedic system of medicine which uses herbal medicines and synthetic derivates is also found to be effective in treating hemoglobin C disease.
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