Granuloma Inguinale

Granuloma Inguinale

Granuloma inguinale is a sexually transmitted disease caused due to bacteria Klebsiella granulomatis. It is characterized by ulcerative lesions on the genital region or perianal region. They appear as painless nodules [granulomas] which get eroded or ulcerated. The other names include donovanosis, granuloma genitoinguinale, granuloma inguinale tropicum.

Causes and risk factors

The disease occurs due to bacterial infection of Klebsiella granulomatis bacteria. It can be transmitted sexually from an infected partner.

Clinical presentation

Patient complains of sores in the genital area. Small, beefy-red bumps occur on the genitals or around the anus. The skin gradually wears away. Sores are usually painless, but they bleed easily if injured. The disease slowly spreads and destroys the genital tissue. Tissue damage may spread to the groin area. The genitals and the adjacent skin lose skin color. Symptoms usually occur after 1 to 10 weeks after getting in contact with the infection.

Investigation

Medical history by the patient and clinical examination by the doctor helps in diagnosis. Culture of tissue sample, biopsy of skin lesions are obtained. Detection of Donavan bodies on histopath slides are diagnostic. Blood test and serum VDRL test is recommended.

Treatment

Treatment consists of administration of antibiotics. Local application may be prescribed. Avoidance of unprotected sex is advised.

Other Modes of treatment

The other modes of treatment can also be effective in treating granuloma inguinale.

Homoeopathy is a science which deals with individualization and considers a person in a holistic way. This science can be helpful in combating the symptoms. Similarly the Ayurvedic system of medicine which uses herbal medicines and synthetic derivates are also found to be effective in treating granuloma inguinale.

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