Horner’s Syndrome

Horner’s Syndrome

Horner’s syndrome is defined as a disorder which affects sympathetic nerve supply of the eye and face. It is characterized by a triad of drooping upper eyelid [ptosis], pupil constriction [miosis], and absence of sweating on one side of face [hemifacial anhidrosis].

Causes and risk factors

The causes of Horner’s syndrome include trauma to the base of skull, stroke, middle ear infection. Pancoast tumour, syringomyelia, cluster headache, spinal cord injury can lead to the disease. Disorders like goiter, thyroid carcinoma, multiple sclerosis, Klumpke paralysis, cavernous sinus thrombosis can cause Horner’s syndrome.

Clinical presentation

It is characterized by a triad of drooping upper eyelid [ptosis], pupil constriction [miosis] and absence of sweating on one side of the face [hemifacial anhidrosis]. Patient of Horner’s syndrome present with symptoms on only one side of the body. They include redness of conjunctiva, partial ptosis, decreased pupil size of the affected eye, enophthalmos [sinking of eyeball into the face]. There can be reduced sweating on the affected side of the face [anhidrosis].

Investigations

Medical history by the patient and clinical examination by the doctor helps in diagnosis. Cocaine drop test is done where cocaine drops are instilled into the eyes. The pupils fail to react to the drops, i.e., no dilatation is seen. Diagnosis is presence of Horner’s syndrome. Other tests include blood and urine test. Chest x-ray is advised. Imaging studies such as MRI of head, neck, and chest may be useful for further evaluation.

Treatment

There is no specific treatment for Horner’s syndrome. It disappears on its own once the underlying cause is treated.

Complications

Horner’s syndrome itself does not cause any complication.

When to Contact a Doctor  

One must consult a doctor if there is abnormality in sensory and motor functions of the eye and face.

Prevention

There is no sure way to prevent Horner’s syndrome.

Systems involved

Central nervous system

Organs involved

Eye, face

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