Causes and risk factors
Macroamylasemia develops due to the formation of immune complexes between amylase and immunoglobulins, i.e., it is an enzyme called amylase which is attached to a protein. As the molecules are large, their filtration through kidney is a slow process. It is associated with disease conditions like malabsorption, celiac disease, ulcerative colitis, rheumatoid arthritis, liver disease, diabetes, lymphoma, and cancer.
Clinical presentation
Macroamylasemia is an asymptomatic benign disease condition. However, associated or underlying disease can present itself with the symptoms.
Investigations
The diagnosis of macroamylasemia can be made by measuring levels of enzyme amylase in blood and urine. Blood tests show high levels, whereas urine shows low levels of amylase in presence with macroamylasemia.
Treatment
No treatment is required as the condition is asymptomatic.
Facts and figures
Not available
Systems involved
Endocrine system, circulatory system.
Organs involved
Pancreas
