Fibrous Dysplasia of Bones

Fibrous Dysplasia of Bones

Fibrous dysplasia is a medical condition characterized by abnormal development of a portion of the bone. Excessive fibrous tissue develops onto the affected bone and continues expanding.

Causative and risk factors

This disease is caused due to a defective gene, after conception has occurred. Hence, it cannot be inherited or passed on to one’s children.

 

Clinical presentation

Commonly affected bones include those of the leg, upper arm, ribs, skull etc. One or more bones may be affected.

Fibrous dysplasia gives rise to painful, tender and swollen bones. The patient experiences frequent occurrence of fractures. The gait of the patient may become unusual. Bone deformities may occur. Other localized symptoms may be present according to the bone affected. Fibrous dysplasia of the bones can give rise to complications like rickets, arthritis, blindness and other sensory problems.

Rarely fibrous dysplasia of bones may be associated with endocrine problems.

 

Investigations  

X-rays of the affected bones are taken. Biopsy of the bone tissue may be advised. Genetic testing may be done. A blood test may reveal elevated levels of serum alkaline phosphatase.

 

Treatment  

There is no cure for fibrous dysplasia of bones. Only symptomatic treatment is offered. Nutritional supplements are given. Treatment of fractures is undertaken with the help of casts or surgeries. Pain-relieving medications are given. Physical therapy is recommended to the patient. Surgery may be necessary to correct bone deformities.

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