Causes and risk factors
The disease is caused as a result of reaction to some specific viral infection. Commonly found viruses that cause this disease are the Epstein-Barr virus, Hepatitis B virus, enterovirus, ECHO virus, respiratory syncytial virus.
Clinical presentation
It affects mainly children between the age 6 to 12 years. An upper respiratory tract infection is followed by a skin eruption. There is fever, malaise, and lymphadenopathy. Red spots [maculopapular rash] develop on thighs, buttocks, outer arms, and then face. The rash is asymmetrical. The individual lesion is bright red in colour, but soon it turns purple. The lesions may develop into fluid filled blisters [vesicles]. Itching is not very common. The lesion becomes purpuric and then may slowly fade away.
Investigation
Medical history by the patient and clinical examination by the dermatologist helps in diagnosis. Routine hemogram must be done. LFT is recommended. Skin biopsy may be advised.
Treatment
No treatment is required as the rash resolves within 2-8 weeks with mild fading. Local topical steroids will help in managing the condition.
Other Modes of treatment
The other modes of treatment can also be effective in treating Gianotti-Crosti syndrome.
Homoeopathy is a science which deals with individualization and considers a person in a holistic way. This science can be helpful in combating the symptoms. Similarly, the Ayurvedic system of medicine which uses herbal medicines and synthetic derivates are also found to be effective in treating Gianotti-Crosti syndrome.
