Salivary Gland Cancer

Salivary Gland Cancer

Every individual has 3 major pairs of salivary glands (parotid, submaxillary, submandibular) and several tiny ones within the mouth and the throat. Their function is to secrete saliva. Salivary gland cancer can begin in any of these glands, though it most commonly affects the parotid gland.

Causative & risk factors

As with most cancers, the cause of salivary gland cancer is not known.

Exposure to radiation therapy in the head and neck region is a known risk factor for development of salivary gland cancer. Occupations involving the use of rubber and asbestos are also associated with a higher risk of developing cancer of the salivary glands.

 

Clinical presentation

Elderly patients are the most commonly affected age group.

A lump can be felt or seen in the region of the cheeks, mouth or neck. The affected salivary gland is usually painful. The affected side of the face may be numb. The relevant muscles become weak. Movements like opening the mouth and swallowing become difficult.

 

Investigations

Imaging studies like a CT, MRI or PET scan is performed to determine the extent of spread of the salivary gland cancer.

Biopsy of the tumor is performed for confirmation.

 

Treatment  

Surgery is the mainstay of treatment for cancer of the salivary glands. It may be followed up with radiation therapy or chemotherapy. Surgery may entail removal of a part or whole of the affected salivary gland along with the surrounding lymph nodes.

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