Subluxation of Lens

Subluxation of Lens

The lens [intraocular lens – IOL] is a crystalline substance located right behind the pupil of the eye. It is supported by suspensory ligaments, [zonules] a ring of fibrous tissue that attaches lens to its equator and connects it to the ciliary body. It is responsible for focusing light. A process called accommodation helps lens to focus on near and approaching objects. Subluxation of lens is a condition in which the portion of supporting zonules is absent and lens lacks support in that part. In this condition, the lens remains in the pupillary area, but there may be tilting of lens or displacement in any meridian.

Causes and risk factors

Causes of subluxation of lens are – congenital ectopia lentis [congenital bilateral subluxation of lens]. Acquired causes include excessive stretching of zonules, degeneration of zonules, and tear of zonules due to trauma or penetrating injury, sports injury, severe blow to the eye or head injury, or accidents. It can occur as a result of major eye surgery.

Clinical presentation

Patient presents with symptoms such as mononuclear diplopia [double vision in one eye], dimness of vision, myopia [short sightedness]. Loss of accommodation is experienced. Signs like unequal depth of anterior chamber, vibration or tremulousness of iris on movement of the eye [iridodonesis] or lens [phacodonesis]. During ophthalmoscopic examination, the edge of lens is visible as dark crescentic line. Indirect ophthalmoscopy may show 2 images of disc due to phakic and aphakic zones in the pupil. Secondary glaucoma may be present in some cases. Photophobia, eye pain, or headache may be the accompanied symptoms.

Investigation

Medical history by the patient and clinical examination by the ophthalmologist helps in diagnosis. Routine ophthalmic examination is done. Visual field testing is recommended.

Treatment

If the lens remains clear and there is no irritative symptom, treatment involves use of glasses to correct the phakic part. Contact lenses to correct vision will also help in managing the condition. In presence of cataract or irritative symptoms, for small zonular tear, extracapsular cataract extraction [ECCE] with posterior chamber intraocular lens [PC IOL] is considered. A capsular tension ring is helpful in some cases. If the zonular tear is more, intracapsular cataract extraction is the treatment of choice followed by anterior vitrectomy. Sometimes scleral fixation posterior chamber -SC PC IOL may be considered.

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